Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0001p183 | (1) | WCRB2014

Early aging of mesenchymal stem/stromal cells derived from the bone marrow of α-1,3-galactosyltransferase knockout pig

Ock Sun A , Oh Keon Bong , Hwang Seongsoo , Im Seo Ki , Kim Youngim

Introduction: The α-1,3-galactosyltransferase knockout (GalT KO) pig is used as the major model for xenotransplantation studies since the knockout of the α-1,3-galactosyl epitope makes pig organ transplantation successful in primates. The homozygous GalT KO pig is produced by a combination of nuclear transfer technique and mating with a heterozygous GalT KO pig. Since most studies using GalT KO pigs have analyzed only the immunological features of their cells, we...